
Approximately four million Canadians are affected by chronic kidney disease (CKD) [1]. CKD is a gradual loss of kidney function over time which can progress to end stage kidney disease (ESKD), a condition that affects about 48,375 Canadians [2]. While there is no cure for kidney failure, renal replacement...

Everolimus (EVR) is a proliferation-signal inhibitor developed as an immunosuppressive therapy following solid-organ transplantation. Among kidney transplant recipients (KTRs), calcineurin inhibitor (CNI)-associated nephrotoxicity remains a major barrier to long-term graft survival. EVR has emerged as...

Safety is a concern for solid-organ transplant (SOT) recipients with systemic inflammatory diseases (SIDs) treated with biologic therapy. This study evaluated the safety of biologic therapy in SOT recipients with SIDs. Methods: This retrospective study between 2000 and 2024 included 20 biologic-treated...

Nocardia are ubiquitous Gram-positive, acid-fast bacteria found worldwide in soil and both fresh- and saltwater. The main route of infection is inhalation [1] but primary cutaneous infection can also occur following traumatic inoculation [2]. These environmental organisms were first described by French...