Kidney TransplantationArchives
GLP-1 receptor agonists for kidney transplant recipients
Kidney Transplantation 1 min.
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are incretin-based therapies with demonstrated efficacy in glycaemic control, weight reduction and cardiovascular and renal protection. Although data in kidney transplant recipients (KTRs) remain limited, the high prevalences of overweight and obesity,...
Cytomegalovirus (CMV)-Specific Cell-Mediated Immunity for Prediction of Postprophylaxis CMV Disease in a Phase 3 Trial of Letermovir Versus Valganciclovir Prophylaxis in Donor CMV-Seropositive/Recipient CMV-Seronegative Kidney Transplant Recipients
Kidney Transplantation 1 min.
QuantiFERON-cytomegalovirus (QFT-CMV) is a standardized assay for the evaluation of cytomegalovirus-specific cell-mediated immunity (CMV-CMI). Objectives: The purpose of this study was to assess the evolution of CMV-CMI posttransplant and the clinical utility of QFT-CMV for the prediction of postprophylaxis...
Neuropsychological Profile in Older Adults with End-Stage Kidney Disease during Kidney Transplantation Evaluation
Kidney Transplantation 1 min.
End-stage chronic kidney disease (CKD) is a significant concern for older adults and is often associated with cognitive impairment (CI). The origin of this CI is multifactorial, involving vascular and metabolic factors. Additionally, renal treatments, including dialysis, may affect cognition. This study...
HLA and non-HLA antibody profiling in the urine of kidney transplant recipients
Kidney Transplantation 1 min.
Kidney transplantation is the preferred therapy for end-stage renal disease (ESRD), yet long-term graft survival remains limited. Effective preservation of transplanted kidneys is essential amid a persistent organ shortage. Post-transplant graft injury arises from both immune and nonimmune mechanisms....
Replacing Mycophenolate Mofetil by Everolimus in Kidney Transplant Recipients to Increase Vaccine Immunogenicity: Results of a Randomized Controlled Trial
Kidney Transplantation 1 min.
Vaccine immunogenicity is reduced in kidney transplant recipients (KTRs), especially in those using mycophenolate mofetil (MMF). Whether replacement of MMF by everolimus improves vaccine immunogenicity is unknown. Methods: KTRs were randomized 1:1 to continue MMF or switch to everolimus. Participants...
