
Propofol is the most widely used short-acting sedative in clinical practice. It inhibits histamine release in the hypothalamus by activating central gamma-aminobutyric acid A (GABA) receptors, blocks N-methyl-D-aspartate receptors, and modulates calcium influx to inhibit postsynaptic neuronal activity...

Tacrolimus is the cornerstone of immunosuppressive therapy in kidney transplantation. However, it exhibits significant pharmacokinetic (PK) variability among patients. Therefore, Population Pharmacokinetic (PopPK) modeling is crucial for personalized tacrolimus treatment. While PopPK models have been...

Kidney transplantation is the definitive treatment for patients with end-stage renal disease. Compared to dialysis, it offers superior survival and quality of life [1, 2–3]. Despite its advantages, the procedure is associated with surgical risks. Among them, wound complications influence graft...

Respiratory viruses are among the most prevalent human pathogens, accounting for a significant proportion of global mortality. These viruses spread rapidly within populations, causing acute infections and, in vulnerable groups, severe or chronic disease [1, 2]. They are characterized by relatively short...