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Neonatal-Perinatal MedicineArchives

Impact of missing electronic fetal monitoring signals on perinatal asphyxia: a multicohort analysis

 Published on 07/05/2025 |  Original article (Full-text)  | Karmakar Debjyoti et al. | npj Digital Medicine 2025; 8(1): 233

Perinatal asphyxia, a serious neonatal outcome, is caused by impaired maternal-fetal gas exchange. It leads to hypoxia, organ damage, and occasionally death, with up to 40% occurring during labor1. It is a leading cause of term newborn morbidity and mortality, responsible for 25% of neonatal deaths,...

The impact of various types of α-thalassemia on perinatal complications and pregnancy outcomes in pregnant women

 Published on 30/04/2025 |  Original article (Full-text)  | Li Yi et al. | Annals of Hematology 2025; 104(3): 1541-50

Thalassemia is the most common clinically inherited monogenic hemolytic anemia caused by a gene mutation or deletion, and it results in the reduced or complete loss of synthesis of the globin chains of hemoglobin. This disorder exhibits an autosomal recessive or incompletely dominant inheritance pattern...

Assessing neonatal brain glymphatic system development using diffusion tensor imaging along the perivascular space and choroid plexus volume

 Published on 23/04/2025 |  Original article (Full-text)  | Peng Ting et al. | BMC Medical Imaging 2025; 25(1): 126

Neonatal brain development represents a critical period characterized by profound structural and functional maturation. During this phase, the brain undergoes near-completion of neuronal migration, rapid synaptogenesis, and accelerated axonal myelination at the microscopic level [1, 2–3]. Macroscopically,...

Incidence of adverse perinatal outcomes in highly vulnerable pregnant women – the Mothers of Rotterdam study

 Published on 16/04/2025 |  Original article (Full-text)  | Mohabier Kajal S. C. et al. | BMC Pregnancy and Childbirth 2025; 25(1): 429

Despite growing advances in health care over the past few decades, health inequalities still remain present worldwide and pose a complex challenge in the field of public health. There is a growing body of literature linking a low socioeconomic status (SES) and accompanying disadvantaged circumstances...

Clinical characteristics, and outcomes of severe neonatal thrombocytopenia: a retrospective cohort study in China

 Published on 09/04/2025 |  Original article (Full-text)  | Shan Yuanyuan et al. | BMC Pediatrics 2025; 25(1): 275

Thrombocytopenia, defined as a platelet count < 150 × 10/µL, occurs in 20 to 35% of patients admitted to the neonatal intensive care unit (NICU) [1]. A small minority (2.1–10%) developed severe neonatal thrombocytopenia (platelet count ≤ 50 × 10/µL),...