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Alzheimer's DiseaseArchives

Brain Volumetric Trajectories in Down Syndrome and Autosomal Dominant Alzheimer Disease
Alzheimer's Disease
 1 min.

 Published on 07/05/2025 |  Original article (Full-text)  | James Tyler Kennedy et al. | Alzheimer's & dementia : the journal of the Alzheimer's Association 2024; 20(S2): 089313

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Blarcamesine in Early Alzheimer Disease Phase 2b/3 Randomized Clinical Trial
Alzheimer's Disease
 1 min.

 Published on 30/04/2025 |  Original article (Full-text)  | Marwan N. Sabbagh et al. | Alzheimer's & dementia : the journal of the Alzheimer's Association 2024; 20(S6): 090729

There are no approved oral disease‐modifying treatments for Alzheimer disease (AD). This study was intended to assess efficacy and safety of blarcamesine (ANAVEX2‐73), an orally available small‐molecule activator of the sigma‐1 receptor (SIGMAR1) designed to exert neuroprotection...

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Solanezumab Treatment for Alzheimer disease : Meta analysis for Non EXPEDITION Trials
Alzheimer's Disease
 1 min.

 Published on 23/04/2025 |  Original article (Full-text)  | Ameer Fadhil Abbas AL Wssawi et al. | Alzheimer's & dementia : the journal of the Alzheimer's Association 2024; 20(S6): 084029

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Evaluating brain age using functional connectivity in autosomal dominant Alzheimer disease
Alzheimer's Disease
 1 min.

 Published on 16/04/2025 |  Original article (Full-text)  | Kiana Angela Macharia et al. | Alzheimer's & dementia : the journal of the Alzheimer's Association 2024; 20(S9): 093634

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Association of brain MRI signatures with Alzheimer Disease CSF biomarkers
Alzheimer's Disease
 1 min.

 Published on 09/04/2025 |  Original article (Full-text)  | You Cheng et al. | Alzheimer's & dementia : the journal of the Alzheimer's Association 2024; 20(S2): 092833

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Association of Enlarged Perivascular Spaces and Measures of Small Vessel and Alzheimer Disease
Alzheimer's Disease
 5 min.

 Published on 31/03/2021 |  Original article (Full-text)  | Gertje, Eske Christiane MD et al. | Neurology 2021; 96(2): e193-e202

Perivascular spaces are CSF-filled cavities that surround the deep perforating arteries in the brain. They are visible on MRIs as they dilate and then are called enlarged perivascular spaces (EVPS).1-4 EPVS are thought to be involved in impaired drainage of interstitial fluid in the white matter.5,6...

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