LymphomaArchives
Prophylactic Tocilizumab prior to infusion of CD19 CAR T-cells reduces therapy-related complications in older lymphoma patients
Lymphoma 3 min.
Until recently, platinum-based chemotherapy, followed by high-dose therapy/autologous hematopoietic stem cell transplant (HD-CT with auto-HSCT), was considered the best option for long-term remission in relapsed/refractory diffuse-large cell B-cell lymphoma (r/r DLBCL) [1]. However, older patients were...
Patient-reported symptom burden and health-related quality of life in patients with aggressive Non-Hodgkin lymphoma: a cross-sectional study
Lymphoma 4 min.
For non-Hodgkin lymphoma (NHL) in China, the disability-adjusted life years (DALY) and age-standardized DALYs increased by 100.9% and 15.6%, respectively, from 1990 to 2019. The age-standardized incidence rates also increased by 21.9% during the same period. Notably, the disease burden was substantially...
Relapsed and refractory peripheral T-cell lymphoma; treatment, challenges and future perspectives
Lymphoma 1 min.
Peripheral T-cell lymphomas (PTCL) comprise a heterogeneous group of 15 different neoplasms in adults. In Europe and North America, PTCL not otherwise specified (PTCL NOS), nodal T follicular helper lymphoma, angioimmunoblastic type (nTFHL-AI), and anaplastic large cell lymphoma (ALCL) either anaplastic...
Treatment patterns and survival outcomes of peripheral T-Cell lymphoma in Saudi Arabia: a 12-Year retrospective analysis
Lymphoma 5 min.
T-cell lymphomas (TCL) are diverse group of non-Hodgkin lymphomas (NHL) that develop from T lymphocytes and natural killer (NK) cells [1]. They account for approximately 5–10% of all lymphomas, with a reported greater incidence in some Asian nations (almost 15–20% of NHLs) [2, 3]. TCL pathophysiological...
Peripheral EBV antigen-specific T cell is dysfunctional in Epstein–Barr virus positive diffuse large B-cell lymphoma
Lymphoma 6 min.
Diffuse large B-cell lymphoma (DLBCL) is a disease characterized by notable clinical and molecular heterogeneity. Beyond prognostic indicators such as the International Prognostic Index (IPI) and revised-IPI (R-IPI), circulating immune parameters and EBV-DNA load, are also considered to have predictive...
