LymphomaArchives
Severe central airway obstruction caused by primary endobronchial B-cell lymphoma: three case reports and literature review
Lymphoma 3 min.
Central airway obstruction (CAO), defined as an occlusion exceeding 50% of the trachea, mainstem bronchi, or lobar bronchi, is associated with severe clinical manifestations and a high mortality rate. It may result from extrinsic compression by surrounding structures, direct invasion from adjacent tumors,...
CD19-directed chimeric antigen receptor T-cell therapy for relapsed or refractory diffuse large B-cell lymphoma: lessons learned from clinical trials and real world evidence
Lymphoma 1 min.
CD19-directed Chimeric Antigen Receptor T-Cell therapy has revolutionized treatment for relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL). Since the approval of axicabtagene ciloleucel, tisagenlecleucel and lisocabtagene maraleucel—CAR-T has offered high response rates and durable...
Pirtobrutinib in the treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma
Lymphoma 1 min.
Pirtobrutinib, a novel noncovalent Bruton's tyrosine kinase (BTK) inhibitor (BTKi) has demonstrated significant potential in overcoming treatment resistance characterized by BTK mutations in chronic lymphocytic leukemia and small lymphocytic leukemia (CLL/SLL). Unlike currently approved covalent BTKi...
Bilateral eyelid masses and enophthalmos as the initial manifestation of diffuse large B-cell lymphoma: a case report
Lymphoma 3 min.
The ocular adnexa refer to the structural components surrounding the eye, including the orbit, eyelids, lacrimal gland, conjunctiva, and lacrimal sac [1]. Although ocular adnexal lymphoma (OAL) is considered an uncommon disease overall, it is among the most prevalent malignancies affecting this anatomical...
