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Alternative splicing patterns in genetic subtypes of diffuse large B-cell lymphoma
Lymphoma
 7 min.

 Published on 06/01/2026 |  Original article (Full-text)  | An Sanyeowool et al. | BMC Cancer 2025; 25(1): 1908

Diffuse large B-cell lymphoma (DLBCL) is the most prevalent subtype of B-cell lymphomas, comprising approximately 30% of all non-Hodgkin lymphoma cases [1]. This aggressive malignancy primarily affects B-lymphocytes, making rapid and effective therapeutic intervention crucial due to its fast growth rate....

Prognostic impact of procarbazine in R-MPV followed by reduced-dose whole-brain radiotherapy and cytarabine for primary central nervous system lymphoma
Lymphoma
 1 min.

 Published on 30/12/2025 |  Original article (Full-text)  | Shuhei Matsumoto et al. | Leukemia & Lymphoma 2025; aop:10.1080/10428194.2025.2604305

The R-MPV regimen—comprising rituximab, methotrexate, procarbazine (PCZ), and vincristine—followed by reduced-dose whole-brain radiotherapy and high-dose cytarabine, is an established treatment for primary central nervous system lymphoma (PCNSL). However, PCZ is occasionally omitted due to...

Multiple skin tumors in a patient treated with orelabrutinib for mantle-cell lymphoma: Case report.
Lymphoma
 1 min.

 Published on 23/12/2025 |  Original article (Full-text)  | Fu, Xuefeng MMa,b et al. | Medicine. Volume 104(50).

Mantle-cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma. Bruton tyrosine kinase inhibitors (BTKi) significantly improve the prognosis of MCL, but their long-term use may induce immunosuppression-related complications, including secondary malignancies. First-generation BTKi such as Ibrutinib...

HIV infection complicated with talaromyces marneffei, tuberculosis, hemophagocytic lymphohistiocytosis and non-Hodgkin lymphoma: a complex case report
Lymphoma
 4 min.

 Published on 16/12/2025 |  Original article (Full-text)  | Fu Wei et al. | BMC Infectious Diseases 2025; 25(1): 1714

HIV-infected individuals with advanced disease are prone to severe immunosuppression, a condition commonly referred to as Acquired Immunodeficiency Syndrome (AIDS) [1], particularly a marked reduction in CD4 + T cell counts, which predisposes them to a wide range of opportunistic infections and malignancies...