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PRDX1 knockdown promotes erastin-induced ferroptosis and impedes diffuse large B-cell lymphoma development by inhibiting the MAPK/ERK pathway
Lymphoma
 7 min.

 Published on 06/05/2025 |  Original article (Full-text)  | Lin Chuanming et al. | BMC Cancer 2025; 25(1): 805

Diffuse large B cell lymphoma (DLBCL) is the most prevalent form of lymphoma among adults globally, accounting for approximately one-third of annual non-Hodgkin lymphoma (NHL) cases [1]. DLBCL demonstrates heterogeneity and aggressiveness, with high malignancy, rapid progression, and poor prognosis [2]....

The validation of advanced-stage Hodgkin lymphoma international prognostic index (A-HIPI) in Turkish patients with classical Hodgkin lymphoma
Lymphoma
 6 min.

 Published on 29/04/2025 |  Original article (Full-text)  | Koca Oguzhan et al. | Annals of Hematology 2025; 104(3): 1765-75

Hodgkin lymphoma (HL) was first described in 1832 by Thomas Hodgkin, who reported seven patients with lymphadenopathy, splenomegaly, fever, night chills, and weight loss [1]. Many clinical prediction models have been developed to discriminate patients and provide the appropriate treatment since HL was...

CD5 and p53 immunohistochemistry: valuable prediction method in molecular typing of CD5-positive diffuse large B-cell lymphoma
Lymphoma
 4 min.

 Published on 22/04/2025 |  Original article (Full-text)  | Wang Han et al. | BMC Cancer 2025; 25(1): 726

Diffuse large B-cell lymphoma (DLBCL) accounts for approximately 40% of non-Hodgkin’s lymphomas, making it the most common B-cell lymphoma [1]. Being an aggressive lymphoma, DLBCL comprising various subtypes, forming a diverse group of diseases with distinct clinical, pathological, and genetic...

Frequent association of malignant effusions in plasmablastic lymphoma: a single-institutional experience of nine cases in Taiwan
Lymphoma
 3 min.

 Published on 15/04/2025 |  Original article (Full-text)  | Chen Bo-Jung et al. | Blood research 2025; 60(1): 22

Plasmablastic lymphoma (PBL) is a rare, aggressive large B-cell lymphoma that is characterized by large atypical B cells with plasmablastic or immunoblastic morphology and a terminal B-cell differentiation phenotype – that is, the expression of plasma cell-related antigens (CD38, CD138, MUM1, PRDM1...