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Integrating transcriptomic and metabolomic analyses to characterize the potential function of SLC1A5 in thyroid cancer

 Published on 08/05/2025 |  Original article (Full-text)  | Shan Fengling et al. | BMC Cancer 2025; 25(1): 816

Thyroid cancer (THCA), as the most common endocrine cancer, has a high incidence in women worldwide [1]. According to the Global Cancer Statistics Report, in China, thyroid cancer is the sixth most prevalent cancer in 2020, with 221,000 new cases [2]. Surgery is the usual treatment for thyroid cancer,...

Choroidal profile in patients with inactive thyroid-associated ophthalmopathy

 Published on 01/05/2025 |  Original article (Full-text)  | Samadi Mahsan et al. | BMC Ophthalmology 2025; 25(1): 243

Thyroid-associated ophthalmopathy (TAO) is an autoimmune condition involving the orbital tissues by cellular infiltration and inflammation that mostly affects patients with autoimmune thyroid disease including Graves’ hyperthyroidism [1, 2]. Upper lid retraction, proptosis, and strabismus are the...

The ability of anexelekto (AXL) expression and TERT promoter mutation to predict radioiodine-refractory differentiated thyroid carcinoma

 Published on 24/04/2025 |  Original article (Full-text)  | Agustina Hasrayati et al. | Diagnostic Pathology 2025; 20(1): 46

Differentiated thyroid carcinoma (DTC) is derived from abnormal follicular cells and constitutes the majority of all thyroid cancer cases, accounting for approximately 90–95% [1]. This category encompasses papillary thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC), Hurthle cell/oncocytic...

A new scoring system for risk stratification of thyroid tumors

 Published on 17/04/2025 |  Original article (Full-text)  | Yuan Ya et al. | BMC Medical Imaging 2025; 25(1): 114

The thyroid gland tumors give rise to the most common endocrine tumors. In 2022, the World Health Organization (WHO) redefined the categories and subtypes of thyroid tumors according to the cell origin, histological and molecular characteristics, allowing a clearer understanding of thyroid tumors. Of...

Comparative analysis of deep learning architectures for thyroid eye disease detection using facial photographs

 Published on 10/04/2025 |  Original article (Full-text)  | Aghajani Amirhossein et al. | BMC Ophthalmology 2025; 25(1): 162

Thyroid eye disease (TED) is a common orbital disease that can be sight-threatening and significantly impact the quality of life, particularly in moderate to severe cases [1, 2]. The diagnosis of TED relies on specific clinical and paraclinical criteria [3]. The initial step in diagnosing TED is a thorough...