Cytomegalovirus reactivation in the lower respiratory tract as an independent risk factor for mortality in critically Ill patients

  • Published on 05/05/2025
  •  Reading time: 4 min.

Kim Joong-Yub 1,2,4, Lee Chan Mi 2, Ahn Yoon Hae 3, Lee Hong Yeul 3, Lee Sang-Min 2,3, Jo Hyeon Jae 2, Choe Pyoeng Gyun 2, Park Wan Beom 2, Kang Chang Kyung 2, Lee Jinwoo 1,2, Kim Nam Joong 2

1 https://ror.org/01z4nnt86 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine Seoul National University Hospital Seoul Republic of Korea
2 https://ror.org/04h9pn542 Department of Internal Medicine Seoul National University Hospital, Seoul National University College of Medicine Seoul Republic of Korea
3 https://ror.org/01z4nnt86 Department of Critical Care Medicine Seoul National University Hospital Seoul Republic of Korea
4 https://ror.org/03vek6s52 Department of Microbiology Harvard Medical School Boston MA USA

Abstract

Background The clinical significance of cytomegalovirus reactivation in the lower respiratory tract (LRT) of critically ill patients remains unclear. We aimed to investigate the association between cytomegalovirus reactivation detected in LRT and intensive care unit (ICU) prognosis.
Methods This study included critically ill patients admitted to a medical ICU at a tertiary referral center in South Korea between January 2021 and June 2023. Cytomegalovirus...

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