Evaluation of the effect of therapeutic plasma exchange on serum cytokine levels in pediatric intensive care unit

Published on 01/06/2025

Reading time: 5 min.

Selen Ceren Cakmak ¹, Hazal Ceren Tugrul ², Dilan Akgun Unlu ¹, Rasit Alkan Albayrak ¹, Gurkan Atay ², Seher Erdogan ², Betul Sozeri ³

¹ Department of Pediatrics, Health Science University Umraniye Research and Training Hospital Istanbul Turkey
² Department of Pediatric Critical Care, Health Science University Umraniye Research and Training Hospital Istanbul Turkey
³ Department of Pediatric Rheumatology, Health Science University Umraniye Research and Training Hospital Istanbul Turkey

Abstract

Introduction Therapeutic plasma exchange (TPE) is crucial for saving lives when used appropriately. This study aimed to assess TPE's impact on tumor necrosis factor‐like weak inducer of apoptosis (TWEAK) protein and IL‐6 levels in critically ill pediatric patients.
Methods Conducted between May 2022 and December 2022, the study observed pediatric intensive care unit (PICU) patients undergoing TPE, recording demographics, lab results, TWEAK,...

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