Understanding chronic pain in Neurofibromatosis Type 1 using the Neurofibromatosis Pain Module (NFPM)

Published on 03/29/2024

Reading time: 4 min.

Frank D. Buono ¹, Kaitlyn Larkin ², William T. Zempsky ^3,4, Lauretta E. Grau ⁵, Staci Martin ⁶

¹ Yale School of Medicine New Haven Connecticut USA
² Northern Illinois University DeKalb Illinois USA
³ Connecticut Children's Medical Center Hartford Connecticut USA
⁴ University of Connecticut School of Medicine Farmington Connecticut USA
⁵ Yale School of Public Health New Haven Connecticut USA
⁶ National Cancer Institute Bethesda Maryland USA

Abstract

Neurofibromatosis Type 1 (NF1) is an autosomal dominant genetic disorder that can cause an individual significant chronic pain (CP). CP affects quality of life and daily functioning, yet there are limited effective treatments for CP within NF1. The current study describes the impact of CP using the Neurofibromatosis Pain Module (NFPM). The NFPM is a self‐reported clinical assessment that evaluates the impact of CP across multiple domains (e.g., interference, severity, tolerance,...

To continue reading this article in Full-Text...

Access request*

* Access is totally free, without commitment or condition. Service exclusively reserved for healthcare professionals.

American Journal of Medical Genetics

Peer-Reviewed Journals A-Z

Search | Advanced search

Get the latest news in Rare Diseases

Receive our newsletter to stay up to date with the latest news in Rare Diseases

Access request

From peer-reviewed journals in Rare Diseases

[space]	Find documents with all the words specified. dopamine homeostasis will get documents with dopamine and homeostasis, found documents must contain the two elements.
OR	Find documents with at least one of the words specified. dopamine OR homeostasis will get documents with word dopamine or homeostasis.
-	The sign - exclude the documents with word or expression specified. dopamine - homeostasis will get the documents with dopamine but without homeostasis. The sign - must be used with others operators.
" "	Find the documents with exactly the expression between the two quotation marks. Example: "symptomatic medication" will find only the documents with "symptomatic medication" in the document.
( )	Brackets are used to group words in a sub expression: (dopamine homeostasis) OR (ergotamine headache)
*	Asterisk is the truncation operator. It can be used as a prefix (with quotation marks) or suffix. *dopa homeo, dopne or "cature"*.