Patients' preferences for chronic lymphocytic leukemia treatment: The CHOICE study
- Published on 14/11/2023
- Reading time: 4 min.
Paolo Sportoletti 1, Luca Laurenti 2, Annalisa Chiarenza 3, Gianluca Gaidano 4, Elisa Albi 5, Francesca Romana Mauro 6, Livio Trentin 7, Daniele Vallisa 8, Fabrizio Pane 9, Antonio Cuneo 10, Francesco Albano 11, Giulia Zamprogna 12, Marta Coscia 13, Alessandro Gozzetti 14, Gianluigi Reda 15, Morena Caira 16, Paola Finsinger 16, Giuliana Gualberti 16, Emilia Iannella 16, Simona Malgieri 16, Stefano Molica 17
1
Institute of Hematology and Center for Hemato‐Oncology Research
University of Perugia and Santa Maria della Misericordia Hospital
Perugia
Italy
2
Hematology Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome
Italy
3
Division of Hematology
Ferrarotto Hospital
Catania
Italy
4
Division of Haematology
Department of Translational Medicine
Università del Piemonte Orientale and Azienda Ospedaliero‐Universitaria Maggiore della Carità
Novara
Italy
5
Strategic Research Programme in CLL
Division of Experimental Oncology
IRCCS Ospedale San Raffaele and Università Vita‐Salute San Raffaele
Milan
Italy
6
Hematology
Department of Translational and Precision Medicine
'Sapienza' University
Rome
Italy
7
Hematology Section
Department of Medicine
Azienda Ospedale Università Padova
Padova
Italy
8
Hematology Unit
Department of Oncology and Hematology
Guglielmo da Saliceto Hospital
Piacenza
Italy
9
Department of Clinical Medicine and Surgery
Federico II University
Naples
Italy
10
Hematology Section
Department of Medical Sciences
Azienda Ospedaliera‐Universitaria
Arcispedale S. Anna
University of Ferrara
Ferrara
Italy
11
Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe‐J)
Hematology and Stem Cell Transplantation Unit
University of Bari "Aldo Moro"
Bari
Italy
12
Department of Hematology
Niguarda Cancer Center
ASST Grande Ospedale Metropolitano Niguarda
Milan
Italy
13
Department of Molecular Biotechnology and Health Sciences
University of Torino and Division of Hematology
A.O.U. Città della Salute e della Scienza di Torino
Torino
Italy
14
Hematology
Department of Medicine, Surgery and Neurosciences
University of Siena
Siena
Italy
15
Hematology Unit
Fondazione IRCCS Ca' Granda Ospedale Maggiore
University of Milan
Milan
Italy
16
AbbVie S.r.l.
Campoverde
Latina
Italy
17
Department of Hematology‐Oncology
Azienda Ospedaliera Pugliese‐Ciaccio
Catanzaro
Italy
Abstract
Chronic lymphocytic leukemia (CLL) therapies differ in efficacy, side effects, route, frequency, and duration of administration. We assessed patient preferences for treatment attributes and evaluated associations with disease stage, treatment line, and socio‐demographic characteristics in a cross sectional, observational study conducted at 16 Italian hematology centers. Study visits occurred between February and July 2020; 401 adult patients with CLL (201 Watch and Wait...
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