Prevalent osteoporosis and fracture risk in patients with hepatic cirrhosis: a systematic review and meta-analysis
- Published on 03/07/2025
- Reading time: 6 min.
Shirinezhad Amirhossein 1, Eshlaghi Fatemeh Mousavi 1, Salabat Dorsa 1, Azarboo Alireza 1, Ardakani Zahra Fotoohi 1, Esmaeili Sina 2, Hoveidaei Amir Human 3, Ghaseminejad-Raeini Amirhossein 1,4
1 https://ror.org/01c4pz451 School of Medicine Tehran University of Medical Sciences Tehran Iran
2 https://ror.org/01c4pz451 Sina University Hospital, Tehran University of Medical Sciences Tehran Iran
3 https://ror.org/01c4pz451 Sports Medicine Research Center, Neuroscience Institute Tehran University of Medical Sciences Tehran Iran
4 https://ror.org/01c4pz451 School of Medicine Tehran University of Medical Sciences, Tehran Province District 6, Pour Sina St, P94V+8MF Tehran Iran
Abstract
Background Hepatic liver cirrhosis can lead to significant systemic complications, including the deterioration of bone health. The resulting bone complications can contribute to a decreased quality of life and increased healthcare burden. This study aimed to systematically review and analyze the risk of osteoporosis, fracture, and changes in bone mineral density (BMD) among patients with hepatic cirrhosis compared to non-cirrhotic healthy controls.
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