The Uncoupling of Disease Activity from Joint Structural Progression in Patients with Rheumatoid Arthritis Treated with Filgotinib
- Published on 04/11/2025
- Reading time: 5 min.
Yoshiya Tanaka 1 , Tatsuya Atsumi 2 , Tsutomu Takeuchi 7 ,8
1 First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu, Japan
2 Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan
7 Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
8 Saitama Medical University, Saitama, Japan
Abstract
Introduction While modern treatments can prevent progressive bone destruction in patients with rheumatoid arthritis (RA) achieving clinical remission, it is unclear whether residual clinical activity may cause or be associated with progressive joint damage. This post hoc analysis evaluated the association between clinical disease activity and structural progression in patients with RA treated with filgotinib (FIL) in FINCH 1 (NCT02889796).
Methods Patients...
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