Full‐house nephropathy in antinuclear antibody‐negative systemic lupus erythematosus: A case report

Published on 08/30/2024

Reading time: 4 min.

Reechashree Dhungana ¹, Bibhav Bashyal ², Sagar Paudel ², Bibek Shrestha ¹, Saket Jha ³, Nishan Bhurtyal ⁴

¹ Maharajgunj Medical Campus, Institute of Medicine Tribhuvan University Kathmandu Nepal
² Department of Internal Medicine, Institute of Medicine Tribhuvan University Teaching Hospital Kathmandu Nepal
³ Department of Internal Medicine Tribhuvan University Teaching Hospital Kathmandu Nepal
⁴ Department of Nephrology Tribhuvan University Teaching Hospital Kathmandu Nepal

Key Clinical Message

Antinuclear antibody‐negative full‐house lupus nephritis though previously reported, is fairly uncommon. Some patients go on to develop antibodies later in the disease course. The presence of RO‐52 antibody in this case suggests an underlying immunological cause. Swift management based on strong clinical suspicion can be life‐saving to the patient.
Abstract Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus...

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