Real‐world safety and efficacy of biologics in elderly patients with psoriasis: A multicenter observational study

  • Published on 07/29/2024
  •  Reading time: 4 min.

Chika Ohata 1, Hisataka Anezaki 2, Tetsuji Yanase 3,4, Eri Katayama 5, Sakae Kaneko 6, Kanami Saito 7, Mariko Yamane 8, Sei Nakamaru 9, Noriko Tsuruta 10, Fusako Okazaki 11, Kotaro Ito 12, Satoko Kikuchi 13, Yuta Koike 14, Takuya Miyagi 15, Kazunari Sugita 16, Takeshi Nakahara 17, Daiki Takezaki 18, Hiroshi Saruwatari 19, Yuichi Yoshida 20, Kentaro Yonekura 21, Yuko Higashi 22, Yu Sawada 23, Yuko Chinuki 24, Kazuki Yamaguchi 25, Shinichi Imafuku 26

1 Department of Dermatology Osaka General Medicine Center Osaka Japan
2 Social/Community Medicine and Health Science Graduate School of Medicine Kobe University Kobe Japan
3 Kamiyacho Yanase Dermatology Clinic Hiroshima Japan
4 Department of Dermatology Hiroshima City North Medical Center Asa Citizens Hospital Hiroshima Japan
5 Department of Dermatology Kurume University School of Medicine Kurume Japan
6 Department of Dermatology Masuda Red Cross Hospital Masuda Japan
7 Department of Dermatology, Faculty of Medicine Oita University Yufu Japan
8 Department of Dermatology Kawasaki Medical School General Medical Center Okayama Japan
9 Department of Dermatology Kansai Medical University Osaka Japan
10 Division of Dermatology Kitakyushu City Yahata Hospital Kitakyusyu Japan
11 Department of Dermatology Okayama City General Medicine Center Okayama Japan
12 Ito Medical Clinic, Dermatology Kitsuki Japan
13 Department of Dermatology Kyushu Central Hospital Fukuoka Japan
14 Department of Dermatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan
15 Department of Dermatology Graduate School of Medicine University of the Ryukyus Nishihara Japan
16 Division of Dermatology, Department of Internal Medicine, Faculty of Medicine Saga University Saga Japan
17 Department of Dermatology, Graduate School of Medical Sciences Kyushu University Fukuoka Japan
18 Department of Dermatology Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan
19 Saruwatari Dermatology Clinic Kagoshima Japan
20 Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine Tottori University Yonago Japan
21 Department of Dermatology Imamura General Hospital Kagoshima Japan
22 Department of Dermatology Kagoshima University Graduate School of Medical and Dental Sciences Kagoshima Japan
23 Department of Dermatology University of Occupational and Environmental Health Kitakyushu Japan
24 Department of Dermatology Shimane University Faculty of Medicine Izumo Japan
25 Department of Dermatology Saiseikai Futsukaichi Hospital Fukuoka Japan
26 Department of Dermatology Fukuoka University Faculty of Medicine Fukuoka Japan

Abstract

Clinical trials of biologics have frequently excluded elderly patients, resulting in inadequate data on their safety and efficacy. Additionally, evidence of their safety and efficacy remains limited, despite some real‐world studies. To assess the safety and efficacy of biologics in elderly patients with psoriasis, we compared these outcomes in younger patients using data from the West Japan Psoriasis Registry (WJPR). The WJPR consists of approximately 30 facilities in Western...

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