Real‐world safety and efficacy of biologics in elderly patients with psoriasis: A multicenter observational study
- Published on 07/29/2024
- Reading time: 4 min.
Chika Ohata 1, Hisataka Anezaki 2, Tetsuji Yanase 3,4, Eri Katayama 5, Sakae Kaneko 6, Kanami Saito 7, Mariko Yamane 8, Sei Nakamaru 9, Noriko Tsuruta 10, Fusako Okazaki 11, Kotaro Ito 12, Satoko Kikuchi 13, Yuta Koike 14, Takuya Miyagi 15, Kazunari Sugita 16, Takeshi Nakahara 17, Daiki Takezaki 18, Hiroshi Saruwatari 19, Yuichi Yoshida 20, Kentaro Yonekura 21, Yuko Higashi 22, Yu Sawada 23, Yuko Chinuki 24, Kazuki Yamaguchi 25, Shinichi Imafuku 26
1
Department of Dermatology
Osaka General Medicine Center
Osaka
Japan
2
Social/Community Medicine and Health Science
Graduate School of Medicine Kobe University
Kobe
Japan
3
Kamiyacho Yanase Dermatology Clinic
Hiroshima
Japan
4
Department of Dermatology
Hiroshima City North Medical Center Asa Citizens Hospital
Hiroshima
Japan
5
Department of Dermatology
Kurume University School of Medicine
Kurume
Japan
6
Department of Dermatology
Masuda Red Cross Hospital
Masuda
Japan
7
Department of Dermatology, Faculty of Medicine
Oita University
Yufu
Japan
8
Department of Dermatology
Kawasaki Medical School General Medical Center
Okayama
Japan
9
Department of Dermatology
Kansai Medical University
Osaka
Japan
10
Division of Dermatology
Kitakyushu City Yahata Hospital
Kitakyusyu
Japan
11
Department of Dermatology
Okayama City General Medicine Center
Okayama
Japan
12
Ito Medical Clinic, Dermatology
Kitsuki
Japan
13
Department of Dermatology
Kyushu Central Hospital
Fukuoka
Japan
14
Department of Dermatology
Nagasaki University Graduate School of Biomedical Sciences
Nagasaki
Japan
15
Department of Dermatology
Graduate School of Medicine University of the Ryukyus
Nishihara
Japan
16
Division of Dermatology, Department of Internal Medicine, Faculty of Medicine
Saga University
Saga
Japan
17
Department of Dermatology, Graduate School of Medical Sciences
Kyushu University
Fukuoka
Japan
18
Department of Dermatology
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Okayama
Japan
19
Saruwatari Dermatology Clinic
Kagoshima
Japan
20
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine
Tottori University
Yonago
Japan
21
Department of Dermatology
Imamura General Hospital
Kagoshima
Japan
22
Department of Dermatology
Kagoshima University Graduate School of Medical and Dental Sciences
Kagoshima
Japan
23
Department of Dermatology
University of Occupational and Environmental Health
Kitakyushu
Japan
24
Department of Dermatology
Shimane University Faculty of Medicine
Izumo
Japan
25
Department of Dermatology
Saiseikai Futsukaichi Hospital
Fukuoka
Japan
26
Department of Dermatology
Fukuoka University Faculty of Medicine
Fukuoka
Japan
Abstract
Clinical trials of biologics have frequently excluded elderly patients, resulting in inadequate data on their safety and efficacy. Additionally, evidence of their safety and efficacy remains limited, despite some real‐world studies. To assess the safety and efficacy of biologics in elderly patients with psoriasis, we compared these outcomes in younger patients using data from the West Japan Psoriasis Registry (WJPR). The WJPR consists of approximately 30 facilities in Western...
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