Role of perirenal adiposity in renal dysfunction among CKD individuals with or without diabetes: a Japanese cross-sectional study
- Published on 03/27/2024
- Reading time: 6 min.
Teruyuki Kono1, Gulinu Maimaituxun1, Hayato Tanabe1, Moritake Higa2, Haruka Saito1, Kenichi Tanaka3, Hiroaki Masuzaki4, Masataka Sata5, Junichiro J. Kazama6, Michio Shimabukuro7
1Department of Diabetes, Endocrinology and Metabolism, Fukushima Medical University School of Medicine, Fukushima, Japan
2Department of Diabetes and Lifestyle-Related Disease Center, Tomishiro Central Hospital, Tomishiro, Okinawa, Japan
3Department of Nephrology and Hypertension, Fukushima Medical University School of Medicine, Fukushima, Japan
4Division of Endocrinology and Metabolism, Second Department of Internal Medicine, University of the Ryukyus Graduate School of Medicine, Nishihara, Okinawa, Japan
5Department of Cardiovascular Medicine, Tokushima University Hospital, Tokushima, Japan
6Department of Nephrology and Hypertension, Fukushima Medical University, Fukushima, Japan
7Department of Diabetes, Endocrinology and Metabolism, Fukushima Medical University, Fukushima, Japan
Correspondence to Dr Michio Shimabukuro; mshimabukuro-ur@umin.ac.jp
Abstract
Introduction It remains unclear whether increased perirenal fat (PRF) accumulation is equally related to renal involvement in patients with and without diabetes mellitus (DM). We evaluated the association between PRF volume (PRFV) and low glomerular filtration rate (GFR) and proteinuria in people with or without type 2 diabetes mellitus (T2DM).
Research design and methods We performed a cross-sectional analysis of 473 individuals without T2DM (non-DM, n=202)...
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