Abstract

Chronic kidney disease (CKD) is increasing in prevalence worldwide posing major implications for public health, such as kidney failure requiring dialysis and increased risk of cardiovascular and all-cause mortality. Diabetic and hypertensive kidney disease represent the two most common causes of CKD. Until a few years ago, lifestyle modifications, blood pressure, glycemic and lipid control, along with ACEi or ARB monotherapy were the only measures for retarding these two diseases...