Using Functional Magnetic Resonance Imaging to Detect Differences in Micturition‐Related Brain Activity Between Volitional and Involuntary Detrusor Contractions
- Published on 01/10/2025
- Reading time: 4 min.
Nhi T. Ha 1, Aidin Abedi 2, Luis Alejandro Morales Ojeda 1,3,4, Stefania Montero 1,3,5, Priya Kohli 1, David Chapman 1, Armita Abedi 6, Petr Gaburak 7, David Ginsberg 1, Richard L. Harvey 8, Charles Y. Liu 2, Kay Jann 9, Evgeniy Kreydin 1,2,3
1
Department of Urology, Keck School of Medicine
University of Southern California
Los Angeles
California
USA
2
Department of Neurological Surgery, USC Neurorestoration Center, Keck School of Medicine
University of Southern California
Los Angeles
California
USA
3
Rancho Research Institute
Rancho Los Amigos National Rehabilitation Center
Downey
California
USA
4
Department of Surgery, Anschutz Medical Center
University of Colorado
Aurora
Colorado
USA
5
Division of Vascular and Endovascular Surgery
Anschutz Medical Center
Aurora
Colorado
USA
6
School of Medicine
Zanjan University of Medical Sciences
Zanjan
Iran
7 Elson S. Floyd College of Medicine
Spokane
Washington
USA
8
Rancho Research Institute
Shirley Ryan AbilityLab
Chicago
Illinois
USA
9
USC Stevens Neuroimaging and Informatics Institute
University of Southern California
Los Angeles
California
USA
Abstract
Introduction Detrusor contractions can be classified as either volitional or involuntary. The latter are a hallmark of urge urinary incontinence. Understanding differences in neuroactivation associated with both types of contractions can help elucidate pathophysiology and therapeutic targets. In this study we aim to compare brain activity associated with voluntary and involuntary detrusor contractions.
Methods Twenty seven stroke survivors with secondary...
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