Clinical distinctions in symptomatology and psychiatric comorbidities between misdiagnosed bipolar I and bipolar II disorder versus major depressive disorder

  • Published on 07/09/2024
  •  Reading time: 6 min.

Wu Zhiguo 1,2,3, Wang Jun 3, Zhang Chen 2, Peng Daihui 2, Mellor David 4, Luo Yanli 1, Fang Yiru 2,5,6,7

1 Department of Psychological Medicine, Renji Hospital Shanghai Jiao Tong University School of Medicine 160 Pujian Road 200127 Shanghai China
2 Division of Mood Disorders, Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine Shanghai China
3 Shanghai Yangpu District Mental Health Center Shanghai University of Medicine and Health Sciences Shanghai China
4 School of Psychology Deakin University Melbourne Australia
5 Department of Psychiatry & Affective Disorders Center Ruijin Hospital, Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road 200025 Shanghai China
6 Shanghai Key Laboratory of Psychotic Disorders Shanghai China
7 CAS Center for Excellence in Brain Science and Intelligence Technology Shanghai China


Background To explore the demographic and clinical features of current depressive episode that discriminate patients diagnosed with major depressive disorder (MDD) from those with bipolar I (BP-I) and bipolar II (BP-II) disorder who were misdiagnosed as having MDD .
Methods The Mini-International Neuropsychiatric Interview (MINI) assessment was performed to establish DSM-IV diagnoses of MDD, and BP-I and BP-II, previously being misdiagnosed as MDD. Demographics,...


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