Epidemiological changes of invasive fungal disease in children with cancer: Prospective study of the National Child Program of Antineoplastic Drugs network, Chile
- Published on 09/04/2024
- Reading time: 4 min.
Marlon Barraza 1, Romina Valenzuela 2, Milena Villarroel 2, Verónica de la Maza 2, Verónica Contardo 3,4, Ana María Álvarez 4,5, Valentina Gutiérrez 4,6, Marcela Zubieta 4,7, Daniela Martínez 4,8, María E. Santolaya 2,4
1
Department of Clinical Pharmacy
Hospital Dr. Luis Calvo Mackenna
Santiago
Chile
2
Department of Pediatrics, Faculty of Medicine, Hospital Dr. Luis Calvo Mackenna
Universidad de Chile
Santiago
Chile
3
Department of Pediatrics, Faculty of Medicine, Hospital Dr. Roberto del Río
Universidad de Chile
Santiago
Chile
4
Committee of Infectious Diseases
National Child Program of Antineoplastic Drugs (PINDA)
Santiago
Chile
5
Department of Pediatrics
Hospital San Juan de Dios
Santiago
Chile
6
Department of Pediatrics, Faculty of Medicine, Hospital Dr. Sótero del Río
Pontificia Universidad Católica
Santiago
Chile
7
Department of Pediatrics
Hospital Dr. Exequiel González Cortés
Santiago
Chile
8
Department of Pediatrics, Faculty of Medicine, Hospital San Borja Arriarán
Universidad de Chile
Santiago
Chile
Abstract
Background Invasive fungal diseases (IFD) are high morbidity and mortality infections in children with cancer suffering episodes of high‐risk febrile neutropenia (HRFN). IFD epidemiology has changed in the last two decades, with an increasing incidence in recent years due to the growing number of immunocompromised children at risk for IFD. The aim of this study was to evaluate the incidence of IFD in children with cancer in the period 2016–2020 compared...
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