A case of subcutaneous metastatic malignant melanoma of the left medial ankle: a case report and review of literature
- Published on 03/10/2025
- Reading time: 3 min.
Workman Lauren 1, Fang Lauren 1, Blazevic Martina 1, Chen Joanna 1, Simman Richard 2,3
1 https://ror.org/01pbdzh19 College of Medicine and Life Sciences University of Toledo 3000 Arlington Ave 43614 Toledo OH USA
2 https://ror.org/01pbdzh19 College of Medicine and Life Sciences, Division of Plastic and Reconstructive Surgery University of Toledo 3000 Arlington Ave 43614 Toledo OH USA
3 https://ror.org/03scrf030 Wound Care Program Jobst Vascular Institute, ProMedica Health Network 2109 Hughes Drive, Suite 400 43606 Toledo OH USA
Abstract
Background Although rare, melanoma confined to the dermis or subcutaneous tissue without evidence of a primary cutaneous site should provoke consideration of melanoma of unknown primary. This diagnosis carries a favorable prognosis when compared with cutaneous metastatic melanoma. Several hypotheses have been proposed for how melanoma of unknown primary develops, two of which were considered in our patient case: (1) spontaneous regression of the primary tumor following...
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