Lithium use and bone health in women with bipolar disorder: A cross‐sectional study

  • Published on 06/02/2024
  •  Reading time: 3 min.

Lana J. Williams 1,2, Bruno Agustini 1, Amanda L. Stuart 1, Julie A. Pasco 1,2,3,4, Jason M. Hodge 1,2, Rasika M. Samarasinghe 1, Ottar Bjerkeset 5, Shae E. Quirk 1, Heli Koivumaa‐Honkanen 6,7, Risto Honkanen 6,7, Jeremi Heikkinen 6,7, Michael Berk 1,2,8,9,10

1 Institute for Mental and Physical Health and Clinical Translation, School of Medicine Deakin University Geelong Victoria Australia
2 Barwon Health University Hospital Geelong Geelong Victoria Australia
3 Department of Medicine–Western Health The University of Melbourne St Albans Victoria Australia
4 School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia
5 Faculty of Nursing and Health Sciences Nord University Levanger Norway
6 Institute of Clinical Medicine, Psychiatry University of Eastern Finland Kuopio Finland
7 Institute of Clinical Medicine, Kuopio Musculoskeletal Research Unit University of Eastern Finland Kuopio Finland
8 Florey Institute for Neuroscience and Mental Health University of Melbourne Parkville Victoria Australia
9 Department of Psychiatry University of Melbourne Parkville Victoria Australia
10 Orygen National Centre of Excellence in Youth Mental Health Parkville Victoria Australia


Introduction Several psychiatric disorders and medications used to treat them appear to be independently associated with skeletal deficits. As there is increasing evidence that lithium possesses skeletal protective properties, we aimed to investigate the association between lithium use and bone health in a group of women with bipolar disorder.
Method Women with bipolar disorder (n = 117, 20+ years) were recruited from south‐eastern...


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