The EKFC equation outperforms the CKD‐EPI and CKiD equations for GFR estimation in adolescent and young adult kidney transplant patients
- Published on 06/05/2024
- Reading time: 4 min.
Chloé Grosyeux 1, Asma Alla 2, Françoise Barbé 3,4, Laurence Derain Dubourg 5, Laurence Chardon 6, Jean‐Louis Guéant 3,4,7, Luc Frimat 2,8, Abderrahim Oussalah 3,4,7, Isabelle Vrillon 1
1
Pediatric Nephrology Department
University Hospital of Nancy
Nancy
France
2
Department of Nephrology
University of Lorraine
Nancy
France
3
Department of Molecular Medicine, Division of Biochemistry, Molecular Biology, and Nutrition
University Hospital of Nancy
Nancy
France
4
Reference Center for Inborn Errors of Metabolism (ORPHA67872)
University Hospital of Nancy
Nancy
France
5
Nephrology, Dialysis, Hypertension and Functional Renal Exploration, Edouard Herriot Hospital
Hospices Civils de Lyon and Université Lyon 1
Lyon
France
6
Department of Biology and Hormonology
Lyon‐Est Hospital
Bron
France
7
INSERM UMR_S 1256, Nutrition, Genetics, and Environmental Risk Exposure (NGERE)
Nancy
France
8
INSERM CIC‐EC CIE6
University of Lorraine
Nancy
France
Abstract
Aim This study evaluated the bias and accuracy of the CKD‐EPI/CKiD and EKFC equations compared with the reference exogenous tracer‐based assessment of glomerular filtration rate (GFR) in adult and pediatric patients according to their renal transplant status.
Methods We assessed the bias and P30 accuracy of the CKD‐EPI/CKiD and EKFC equations compared with iohexol‐based GFR measurement.
Results In...
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