Roles of negative emotions and personality traits in psoriasis vulgaris: A mendelian randomization study

  • Published on 06/10/2024
  •  Reading time: 3 min.

Min Zhang, Yu Hu, Lihao Chen, Hongying Chen, Dan Huang, Chao Luan, Jiaan Zhang, Kun Chen

Hospital for Skin Diseases Institute of Dermatology Chinese Academy of Medical Science & Peking Union Medical College Nanjing Jiangsu China


Background Many studies have indicated that negative emotions and personality traits are related to psoriasis, though few have provided causal evidence.
Methods Our analysis utilized 15 genome‐wide association study datasets to identify instrumental variables associated with negative emotions, personality traits and psoriasis vulgaris. Two‐sample Mendelian randomization was conducted to identify the causal associations of negative emotions...


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