Promising immunomodulators for management of substance and alcohol use disorders
- Published on 06/11/2024
- Reading time: 4 min.
Amanda M. Acuña a , Connor Park b , Jonna M. Leyrer-Jackson b & M. Foster Olive a,*
a Department of Psychology, Behavioral Neuroscience and Comparative Psychology Area, Arizona State University, Tempe, Arizona, USA
b Department of Medical Education, Creighton University School of Medicine - Phoenix Campus, Phoenix, Arizona, USA
CONTACT M. Foster Olive mailto:foster.olive@asu.edu Department of Psychology, Behavioral Neuroscience and Comparative Psychology Area, Arizona State University, 950 S. McAllister Ave, Tempe, AZ 85287, USA
Abstract
Introduction The neuroimmune system has emerged as a novel target for the treatment of substance use disorders (SUDs), with immunomodulation producing encouraging therapeutic benefits in both preclinical and clinical settings.
Areas covered In this review, we describe the mechanism of action and immune response to methamphetamine, opioids, cocaine, and alcohol. We then discuss off-label use of immunomodulators as adjunctive therapeutics in the treatment...
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