Kidney Paired Donation—European Transnational Experience in Adults and Opportunities for Pediatric Kidney Transplantation

  • Published on 09/04/2024
  •  Reading time: 5 min.

Georg A. Böhmig 1, Thomas Müller‐Sacherer 2, Ondrej Viklicky 3

1 Division of Nephrology and Dialysis, Department of Medicine III Medical University of Vienna Vienna Austria
2 Department of Pediatrics Medical University Vienna Vienna Austria
3 Department of Nephrology, Transplant Center Institute for Clinical and Experimental Medicine Prague Czech Republic

Abstract

Background Live donor kidney transplantation is considered the optimal choice for renal replacement therapy, providing established benefits, such as superior patient survival and improved quality of life. However, immunological challenges, including ABO blood group incompatibility and, particularly, donor‐specific HLA antibodies, may impact long‐term outcomes considerably or even prevent safe direct transplantation with the intended donor.
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