Depression as a risk factor for osteoporosis independent of sarcopenia in hemodialysis patients: findings from a multicenter cross-sectional study

  • Published on 01/29/2025
  •  Reading time: 5 min.

Hu Xiaohua 1, Ye Xianwu 1, Chen Haimin 2, Wu Bibo 1, Guo Qi 3, Yu Chen 4, Ding Wei 5, Niu Jianying 6, Zhao Junli 7, Qi Hualin 8, Zhang Suhua 9, Xue Cheng 10, Zhang Liming 1

1 Department of Nephrology Zhabei Central Hospital of Jing’an District No. 619 Zhonghua New Road 20070 Shanghai China
2 Department of Hematology and Oncology Zhabei Central Hospital of Jing’an District Shanghai China
3 https://ror.org/03ns6aq57 Department of Rehabilitation Medicine Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital Shanghai China
4 https://ror.org/03rc6as71 Department of Nephrology, Tongji Hospital School of Medicine Tongji University Shanghai China
5 https://ror.org/0220qvk04 Department of Nephrology, Shanghai Ninth People’s Hospital Shanghai Jiao Tong University School of Medicine Shanghai China
6 https://ror.org/013q1eq08 Department of Nephrology The Fifth People’s Hospital of Shanghai, Fudan University Shanghai China
7 https://ror.org/03ns6aq57 Department of Nephrology Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital Shanghai China
8 https://ror.org/02hx18343 Department of Nephrology Shanghai Pudong New Area People’s Hospital Shanghai China
9 https://ror.org/00kkxne40 Department of Nephrology Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine Suzhou China
10 https://ror.org/0103dxn66 Department of Nephrology, Shanghai Changzheng Hospital Second Military Medical University (Naval Medical University) Shanghai China

Abstract

Background Osteoporosis and sarcopenia frequently occur in patients with end-stage renal disease undergoing hemodialysis (HD), and depression is also a common mental health issue in this population. Despite the prevalence of these conditions, the interrelationships among them remain poorly understood in HD patients.
Methods In this multicenter cross-sectional study, 858 HD patients from 7 dialysis centers were recruited. Bone mineral density (BMD) was assessed...

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