Novel chemokine biomarkers in melanoma†
- Published on 07/08/2024
- Reading time: 2 min.
Alessio Giubellino 1,2, Sara E Hamilton 1,2,3
1
Department of Laboratory Medicine and Pathology
University of Minnesota
Minneapolis
MN
USA
2
Masonic Cancer Center
University of Minnesota
Minneapolis
MN
USA
3
Center for Immunology
University of Minnesota
Minneapolis
MN
USA
Abstract
The melanoma tumor microenvironment is a complex milieu of cancer, inflammatory, and stromal cells. In this context, chemokines play a pivotal role in recruiting inflammatory cells and influence the tumor, exerting both pro‐tumorigenic and anti‐tumoral roles. Interactions between these cells is what ultimately hold together and transform the tumor into an efficient machine. A recent study found that chemokines CCL8, CCL15, and CCL20 were upregulated in melanoma cells...
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