Gut microbiota composition and changes in patients with sepsis: potential markers for predicting survival

  • Published on 08/02/2024
  •  Reading time: 5 min.

Luan Feiyu 1, Zhou Yang 1, Ma Xiaohui 1, Li Yue 2, Peng Yahui 1, Jia Xiaonan 1, Li Nana 1, Wang Xibo 1, Luo Yinghao 1, Man Mingyin 1, Zhang Qianqian 1, Wang Chunying 1, Yu Kaijiang 1, Zhao Mingyan 1, Wang Changsong 1

1 Departments of Critical Care Medicine the First Affiliated Hospital of Harbin Medical University, Harbin Medical University 150001 Harbin Heilongjiang China
2 Departments of Critical Care Medicine the Second Affiliated Hospital of Harbin Medical University, Harbin Medical University 150081 Harbin Heilongjiang China

Abstract

Background Sepsis can cause immune dysregulation and multiple organ failure in patients and eventually lead to death. The gut microbiota has demonstrated its precise therapeutic potential in the treatment of various diseases. This study aimed to discuss the structural changes of the gut microbiota in patients with sepsis and to analyze the differences in the gut microbiota of patients with different prognoses.
Methods We conducted a multicenter study in...

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