Effect of high-dose N-acetyl cysteine on the clinical outcome of patients with diabetic peripheral neuropathy: a randomized controlled study
- Published on 03/12/2025
- Reading time: 7 min.
Emara Sherien Mohamed 1, Fahmy Sarah Farid 2, AbdelSalam Mona Mohamed 3, Wakeel Lamia Mohamed El 2
1 https://ror.org/0066fxv63 Clinical Pharmacy Department, Faculty of Pharmacy British University Cairo Egypt
2 https://ror.org/00cb9w016 Clinical Pharmacy Department, Faculty of Pharmacy Ain Shams University Cairo Egypt
3 https://ror.org/00cb9w016 Department of Endocrinology, Faculty of Medicine Ain Shams University Hospitals Cairo Egypt
Abstract
Background Diabetic peripheral neuropathy (DPN) is a vastly common and bothersome disorder with a clinically challenging course of treatment affecting patients with diabetes. This study aimed to evaluate the efficacy and safety of high dose oral N-acetyl cysteine (NAC) as adjuvant therapy on clinical outcome of DPN.
Methods A prospective, randomized, parallel, open label, controlled clinical trial. Ninety eligible DPN patients were randomly assigned to...
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