Pragmatic considerations in clinical biomarker testing for Alzheimer disease

  • Published on 03/12/2025
  •  Reading time: 4 min.

Suzanne E. Schindler 1, Madeline Paczynski 2, Dawn Ellington 2, B. Joy Snider 2

1 Knight Alzheimer Disease Research Center, St. Louis, MO USA
2 Knight Alzheimer Disease Research Center, Saint Louis, MO USA

Abstract

Background With the traditional FDA approval of lecanemab for treatment of early symptomatic Alzheimer disease (AD), there has been a surge in demand for clinical AD biomarker testing. While amyloid PET, cerebrospinal fluid (CSF) biomarkers, and AD blood tests are all clinically available, each have different benefits and limitations affecting their real‐world use.
Methods Pragmatic issues affecting usage of different AD biomarker testing modalities...

ContentGeneMD

To continue reading this article in Full-Text...

* Access is totally free, without commitment or condition. Service exclusively reserved for healthcare professionals.

Peer-Reviewed Journals A-Z

Search | Advanced search

Get the latest news in Neurology

Receive our newsletter to stay up to date with the latest news in Neurology