Pragmatic considerations in clinical biomarker testing for Alzheimer disease
- Published on 03/12/2025
- Reading time: 4 min.
Suzanne E. Schindler 1, Madeline Paczynski 2, Dawn Ellington 2, B. Joy Snider 2
1 Knight Alzheimer Disease Research Center, St. Louis, MO USA
2 Knight Alzheimer Disease Research Center, Saint Louis, MO USA
Abstract
Background With the traditional FDA approval of lecanemab for treatment of early symptomatic Alzheimer disease (AD), there has been a surge in demand for clinical AD biomarker testing. While amyloid PET, cerebrospinal fluid (CSF) biomarkers, and AD blood tests are all clinically available, each have different benefits and limitations affecting their real‐world use.
Methods Pragmatic issues affecting usage of different AD biomarker testing modalities...
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