Peripheral arterial rather than venous blood is a better source of circulating tumor cells in early lung cancer

  • Published on 08/02/2024
  •  Reading time: 4 min.

Zhen‐dan Wang 1,2, Yi‐fei Feng 3, Yu‐shuo Wang 4, Ying Ma 5, Jiyan Liu 5, Dihua Li 5, Sheng Li 5,6, Guo‐dong Zhang 2

1 Department of Thoracic Surgery Shandong University Cancer Center Jinan China
2 Department of Thoracic Surgery, Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical Sciences Jinan China
3 School of Clinical and Basic Medicine Shandong First Medical University Jinan China
4 Department of Primary Care and Population Health, Institute of Epidemiology and Public Health London's Global University London UK
5 Shandong Pharmaceutical Research Institute Jinan China
6 Shandong First Medical University and Shandong Academy of Medical Sciences Jinan China

Abstract

Background Circulating tumor cells (CTCs) play a crucial role in the early diagnosis and prognosis of lung cancer. Identification of a more suitable sample source could be a breakthrough towards enhancing CTC detectability in early‐stage lung cancer. We investigated the differences in detectable CTCs between peripheral arterial and venous blood in early‐ and mid‐stage lung cancer patients undergoing surgery and analyzed the association between clinicopathological...

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