Optic nerve sheath enhancement on orbital MRI in giant cell arteritis

Published on 01/03/2025

Reading time: 4 min.

Rebka K Ephrem¹, Suyash Mohan², Ryan Rebello³, Rui Liang¹, Robert Kurtz², Jae W Song², Madhura A Tamhankar⁴, Rennie L Rhee⁵

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA
²Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
³Department of Diagnostic Imaging, St Joseph's Healthcare Hamilton, Hamilton, Ohio, Canada
⁴Department of Neuro-ophthalmology; Departments of Ophthalmology and Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
⁵Medicine - Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

Correspondence to Dr Rennie L Rhee; rennie.rhee@pennmedicine.upenn.edu

Abstract

Background Differentiating arteritic anterior ischaemic optic neuropathy (A-AION) due to giant cell arteritis (GCA) from non-arteritic anterior ischaemic optic neuropathy (NA-AION) may pose a diagnostic challenge. Our study aimed to assess the use of standard orbital MRI in distinguishing ocular manifestations of GCA from NA-AION.
Methods This study included 25 consecutive patients (11 GCA, 14 NA-AION) who underwent contrast-enhanced orbital MRIs within...

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British Journal of Ophthalmology

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