Hippocampal avoidance whole-brain radiotherapy with simultaneous integrated boost in lung cancer brain metastases and utility of the Hopkins verbal learning test for testing cognitive impairment in Chinese patients: a prospective phase II study

  • Published on 08/01/2024
  •  Reading time: 4 min.

Li Zhuoran , Wang Jianyang , Deng Lei , Zhai Yirui , Zhang Tao , Bi Nan , Wang Jingbo , Wang Xin , Liu Wenyang , Xiao Zefen , Chen Dongfu , Lv Jima , Feng Qinfu , Wang Wenqing , Zhou Zongmei

https://ror.org/02drdmm93 Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College No.17 Panjiayuan Nanli, Chaoyang District 100021 Beijing P.R. China

Abstract

Background This study aimed to evaluate the efficiency of hippocampal avoidance whole-brain radiotherapy with a simultaneous integrated boost (HA-WBRT-SIB) treating brain metastases (BM) and utility of the Hopkins Verbal Learning Test-Revised (HVLT-R) (Chinese version) in Chinese lung cancer patients.
Methods Lung cancer patients with BM undergone HA-WBRT-SIB at our center were enrolled. Brain magnetic resonance imaging, The HVLT total learning score, and...

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