Non-genetic factors and breast cancer: an umbrella review of meta-analyses

  • Published on 08/01/2024
  •  Reading time: 7 min.

Yiallourou Anneza 1, Pantavou Katerina 1, Markozannes Georgios 2,3, Pilavas Antonis 1, Georgiou Andrea 1, Hadjikou Andria 1, Economou Mary 1, Christodoulou Neophytos 4, Letsos Konstantinos 1, Khattab Elina 1, Kossyva Chrystalleni 1, Constantinou Maria 1, Theodoridou Melanie 1, Piovani Daniele 5,6, Tsilidis Konstantinos Κ. 2,3, Bonovas Stefanos 5,6, Nikolopoulos Georgios K. 1

1 https://ror.org/02qjrjx09 Medical School, University of Cyprus P.O. Box 20537 1678 Nicosia Cyprus
2 https://ror.org/041kmwe10 Department of Epidemiology and Biostatistics School of Public Health, Imperial College London SW7 2AZ London UK
3 https://ror.org/01qg3j183 Department of Hygiene and Epidemiology University of Ioannina School of Medicine 45110 Ioannina Greece
4 Royal Papworth Hospital Papworth Rd, Trumpington CB2 0AY Cambridge UK
5 https://ror.org/020dggs04 Department of Biomedical Sciences Humanitas University 20072 Milan Italy
6 https://ror.org/05d538656 IRCCS Humanitas Research Hospital 20089 Milan Italy

Abstract

Background Previous research has found associations between various non-genetic factors and breast cancer (BrCa) risk. This study summarises and appraises the credibility of the available evidence on the association between non-genetic factors and BrCa risk.
Methods We conducted an umbrella review of meta-analyses. Medline, Scopus, and the Cochrane databases were systematically searched for meta-analyses examining non-genetic factors and BrCa incidence...

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