Adipokine isthmin-1 is a potential predictor of abnormal urine Na+ excretion and insulin resistance for primary hypertension
- Published on 03/10/2025
- Reading time: 4 min.
Deng Chunyan 1,2, Zhou Xiaoxin 1,3, Zhang Longlong 1,4, You Qiuxiang 2, Liu Cong 2, Zhang Yundong 2, Yang Jian 1,3
1 https://ror.org/017z00e58 Research Center for Metabolic and Cardiovascular The Third Affiliated Hospital of Chongqing Medical University 401120 Chongqing China
2 https://ror.org/017z00e58 Department of Neurology The Third Affiliated Hospital of Chongqing Medical University 401120 Chongqing China
3 https://ror.org/017z00e58 Department of Clinical Nutrition The Third Affiliated Hospital of Chongqing Medical University 401120 Chongqing China
4 https://ror.org/017z00e58 Department of Endocrinology The Third Affiliated Hospital of Chongqing Medical University 401120 Chongqing China
Abstract
Background Isthmin-1 (ISM1) plays an important role in maintaining glucose homeostasis and lipid metabolism. However, the relationship between circulating ISM1 and hypertension remains unclear. This study was aimed to investigate the association between serum ISM1 levels and blood pressure and evaluate value of circulating ISM1 for predicting abnormal Na+ excretion and insulin resistance.
Methods Four hundred sixty-eight individuals newly diagnosed...
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