Analysis of the effect of fecal SDC2, ADHFE1 and PPP2R5C gene methylation test for screening colorectal cancer in the Otog Front Banner

  • Published on 05/06/2025
  •  Reading time: 5 min.

Zeng Fan 1, Chen Shiiu 1, Zhu Xuli 2, Chen Jinrun 2, Lan Maochong 3, Chen Runxiang 1, Zhang Daya 1, Chen Chen 1, Huang Shimei 1, Li Da 1, Zhang Xiaodong 1, Bai Feihu 4,5

1 https://ror.org/004eeze55 The Second School of Clinical Medicine, Hainan Medical University 571199 Haikou China
2 https://ror.org/035adwg89 Otog Front Banner Peoples Hospital, Inner Mongolia Autonomous Region, China, 016200 016200 Ordos China
3 Graduate School, Jiujiang College 332001 Jiujiang China
4 https://ror.org/004eeze55 Department of Gastroenterology The Second Affiliated Hospital of Hainan Medical University Yehai Avenue, #368, Longhua District 570216 Haikou Hainan Province China
5 The Gastroenterology Clinical Medical Center of Hainan Province 570216 Haikou China

Abstract

Objective The incidence of colorectal cancer (CRC) is gradually increasing, making the prevention and early detection of CRC a global priority. The purpose of this study is to evaluate the effect of fecal SDC2, ADHFE1, and PPP2R5C gene methylation on the screening of early CRC in the Otog Front Banner.
Methods This is a retrospective study that collected and analyzed data from the early colorectal cancer screening program conducted in five community health...

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