Copper in colorectal cancer: From copper‐related mechanisms to clinical cancer therapies
- Published on 07/04/2024
- Reading time: 11 min.
Yuhong Wang1,2,3, Pei Pei4, Kai Yang 3,4, Lingchuan Guo 3, Yuan Li 1,2
1
Department of Pathology
Fudan University Shanghai Cancer Center
Shanghai
China
2
Department of Oncology
Shanghai Medical College
Fudan University
Shanghai
China
3
Department of Pathology
The First Affiliated Hospital of Soochow University
Suzhou
China
4
State Key Laboratory of Radiation Medicine and Protection
School of Radiation Medicine and Protection & School for Radiological and Interdisciplinary Sciences (RAD‐X)
Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions
Soochow University
Suzhou
Jiangsu
China
Abstract
Copper, a trace element and vital cofactor, plays a crucial role in the maintenance of biological functions. Recent evidence has established significant correlations between copper levels, cancer development and metastasis. The strong redox‐active properties of copper offer both benefits and disadvantages to cancer cells. The intestinal tract, which is primarily responsible for copper uptake and regulation, may suffer from an imbalance in copper homeostasis. Colorectal...
To continue reading this article in Full-Text...
Peer-Reviewed Journals A-Z
Search | Advanced search
Get the latest news in Oncology
Receive our newsletter to stay up to date with the latest news in Oncology
